Glycyrrhizin modulates cortisol metabolism by inhibiting 11β-HSD2 enzyme, thus extending cortisol’s half-life. It soothes mucous membranes, reduces inflammation, and acts as a synergist in herbal blends by enhancing absorption and activity.
Used for leaky gut, GERD, ulcers, adrenal fatigue, chronic fatigue syndrome, sore throat, bronchitis, and viral infections. Deglycyrrhizinated form (DGL) is preferred for long-term GI use.
Used in Ayurvedic, Chinese, and Middle Eastern medicine for thousands of years for vitality, longevity, coughs, ulcers, and hormone balancing. A key component in over 50% of Traditional Chinese Medicine formulas.
Consumed as teas, tinctures, powdered extracts, capsules, or decoctions. DGL used specifically for GI issues.
Avoid in hypertension, kidney disease, liver disorders, or with corticosteroid medications unless under supervision.
May increase effects of corticosteroids and interfere with potassium levels.
