Allantoin promotes cell proliferation and accelerates epithelial and connective tissue repair. Mucilage soothes inflammation, while tannins tighten and protect tissue. PAs, if consumed internally, can damage liver cells.
Used externally for sprains, bone fractures, bruises, inflamed joints, burns, eczema, and tissue regeneration after trauma.
Known as “knitbone,” Comfrey has a long history in folk medicine for setting broken bones, healing wounds, and calming inflammation. Poultices and compresses were standard remedies in medieval and herbalist practice.
Used topically as a poultice, cream, oil infusion, or compress. Internal use is discouraged unless PA-free extract is verified.
Do not use internally due to risk of liver toxicity (from PAs). Avoid applying to open wounds without professional guidance.
None known externally. Internal use may amplify hepatotoxicity with other medications.
