Digestive 120’s

This Digestive and Colon supplement works by combining a variety of botanical ingredients, each with distinct properties and constituents that collectively support digestive and colon health. These components contribute antibacterial, antifungal, anti-inflammatory, and soothing effects, addressing a range of gastrointestinal concerns. By promoting intestinal barrier function, regulating gut microbiota, and alleviating digestive discomfort, this supplement offers comprehensive support to the digestive and colon systems.

The digestive system is a complex network of organs and processes in the body responsible for breaking down food and absorbing nutrients to provide energy and support bodily functions.

It begins when food is ingested and follows a carefully orchestrated path through various stages:

Mouth: Digestion begins in the mouth, where teeth grind and break down food into smaller pieces, while saliva mixes with the food to start the chemical breakdown of carbohydrates.

Esophagus: The chewed food is then swallowed and moves down the esophagus through a process called peristalsis, which involves muscular contractions that push the food toward the stomach.

Stomach: Upon reaching the stomach, food encounters gastric juices containing hydrochloric acid and digestive enzymes. These substances create an acidic environment that further breaks down food and kills harmful bacteria. The resulting mixture, called chyme, is slowly released into the small intestine.

Small Intestine: Most digestion and nutrient absorption occur in the small intestine. Here, chyme is mixed with bile from the liver and digestive enzymes from the pancreas, allowing for the breakdown of fats, proteins, and carbohydrates. Nutrients are then absorbed into the bloodstream through the intestinal walls.

Large Intestine (Colon): After passing through the small intestine, any remaining undigested food enters the large intestine, or colon. The colon primarily absorbs water and electrolytes, converting the remaining contents into faeces. The colon plays a crucial role in the digestive process, and diseases affecting it can have a significant impact on health.

Some common colon-related diseases include:

Colitis: Colitis refers to inflammation of the colon. It can result from infections, autoimmune reactions, or inflammatory bowel diseases like Crohn's disease and ulcerative colitis. Symptoms include abdominal pain, diarrhea, and rectal bleeding.

Diverticulitis: Diverticulitis is the inflammation or infection of small pouches (diverticula) that can form in the colon. It often leads to abdominal pain, fever, and changes in bowel habits.

Colon Cancer: Colon cancer is the development of malignant tumours in the colon. Early detection is crucial for successful treatment, as symptoms may not appear until the disease is advanced.

Irritable Bowel Syndrome (IBS): IBS is a functional gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel habits. While it doesn't cause structural damage to the colon, it can significantly impact a person's quality of life.

Constipation:
Although not a disease itself, chronic constipation can lead to discomfort and complications, such as Hemorrhoids and diverticulosis, where small pouches form in the colon wall.

The connection between "leaky gut" and "leaky brain" is an area of growing interest in medical research, and it centers on the concept of increased intestinal permeability and its potential impact on the blood-brain barrier (BBB).

Leaky Gut (Increased Intestinal Permeability): Leaky gut refers to a condition in which the lining of the small intestine becomes more permeable than it should be. Normally, the intestinal lining acts as a barrier, allowing the absorption of essential nutrients while preventing the entry of harmful substances like bacteria and toxins into the bloodstream. When this barrier is compromised, as in the case of leaky gut, these harmful substances can leak through the intestinal wall and enter the bloodstream. This can trigger an immune response, leading to inflammation and various health issues.

Leaky Brain (Blood-Brain Barrier Permeability):
The blood-brain barrier (BBB) is a highly selective membrane that separates the bloodstream from the brain and spinal cord. Its primary role is to protect the brain by allowing only specific molecules to pass through while blocking potentially harmful substances. Like the gut lining, the BBB can also become more permeable under certain conditions. When the BBB becomes "leaky," it allows substances that would typically be kept out to enter the brain, potentially leading to neuroinflammation and cognitive issues.

The connection between leaky gut and leaky brain lies in the idea that inflammation and dysfunction in one barrier (the gut) can potentially contribute to inflammation and dysfunction in the other barrier (the BBB). While this concept is still an area of ongoing research, some theories suggest that the chronic inflammation and release of proinflammatory molecules associated with leaky gut may trigger similar processes in the brain, thereby increasing the permeability of the BBB.

Several factors have been proposed as potential contributors to both leaky gut and leaky brain, including chronic stress, dietary factors (such as a high-sugar or high-fat diet), and certain medical conditions. However, it's important to note that the precise mechanisms and causal relationships between these conditions are not yet fully understood, and more research is needed to establish definitive connections.

Ingredients which are traditionally used for this disorder
Technical info:

Aloe Ferox (Aloe ferox): Aloe ferox contains anthraquinones and tannins, conferring antibacterial and antifungal properties. It plays a role in colon health and alleviates constipation, acting as an astringent and anti-inflammatory agent. However, extended usage of aloe as a single herb may potentially induce bowel laziness, impacting regular bowel movements.

Bilberry (Vaccinium myrtillus): Bilberry's anthocyanin compounds are known to enhance intestinal barrier function and modulate the gut microbiota. These actions support colon health by promoting a balanced microbial environment in the digestive tract.

Buchu (Agathosma betulina): Buchu boasts a rich history of traditional use as a digestive and stomach tonic. It contains essential oils like pulegone and menthone, imparting anti-spasmodic properties that alleviate nausea, indigestion, and flatulence. Moreover, it possesses cleansing properties that help maintain a favourable balance of beneficial gut bacteria.

Calendula (Calendula officinalis): Calendula, enriched with flavonoids, triterpenoids, and saponins, offers benefits in wound healing, potentially aiding in the repair of digestive sores.

Cancer Bush (Sutherlandia frutescens): Research into Sutherlandia, encompassing canavanine, pinitol, and various flavonoids, explores its potential applications in digestive and colon health.

Cancer Bush (Sutherlandia frutescens): Research is ongoing regarding the potential application of Sutherlandia, which contains canavanine and flavonoids, in addressing cancer-related inflammation and digestive concerns.

Catnip (Nepeta cataria): Catnip, with constituents such as nepetalactone and nepetalic acid, functions as a digestive stimulant, promoting appetite and alleviating issues like flatulence, indigestion, and colic. Additionally, it may address stress-related digestive discomfort.

Chamomile (Matricaria chamomilla): Chamomile is renowned for its digestive relaxant properties, attributed to flavonoids, terpenoids, and essential oils. It effectively manages various gastrointestinal disturbances, including flatulence, indigestion, diarrhea, and nausea.

Dandelion (Taraxacum officinale): Dandelion is rich in bitter principles, inulin, flavonoids, and terpenes, facilitating relief from constipation, supporting food transit through the digestive tract, purifying the blood, and aiding kidney detoxification.

Fulvic Acid: Fulvic acid, a natural compound derived from humus, may assist the digestive system by chelating minerals and increasing their bioavailability, thus enhancing nutrient absorption. Its unique molecular structure allows it to form complexes with various minerals, potentially improving their solubility and uptake in the gastrointestinal tract, ultimately supporting better nutrient utilization.

Hydrangea Root (Hydrangea arborescens): Hydrangea root contains hydrangin, saponins, and flavonoids, potentially playing a role in protecting against autoimmune-driven inflammatory responses. Historically, it has been used to address urinary tract infections and stones.

Marshmallow Leaves (Althaea officinalis) and Marshmallow Root (Althaea officinalis): Marshmallow's mucilage, flavonoids, and polysaccharides exhibit mucous membrane-soothing properties across the gastrointestinal tract. This makes it valuable in conditions such as ulcers, colitis, gastritis, acid reflux, and heartburn.

Passion Flower (Passiflora incarnata): Passion flower's alkaloids, flavonoids, and coumarins have sedative effects, potentially beneficial for alleviating stomach problems, including stomach ulcers and discomfort associated with the nervous system.

Plantain (Plantago major): Plantain's iridoids, flavonoids, and mucilage contribute to stomach ulcer healing and regulation of digestive tract movement, promoting bowel regularity and addressing various digestive issues with anti-inflammatory properties.

Psyllium (Plantago ovata): Psyllium husk is a rich source of soluble fiber, absorbing water in the gut and functioning as a bulk-forming laxative. It promotes regularity without excessive flatulence, making it useful for easing constipation and maintaining overall digestive health.

Resveratrol (Polygonum cuspidatum): Resveratrol, a polyphenol, influences the gut microbiome and offers protection to intestinal cells, preventing damage induced by dietary toxins, thereby contributing to gastrointestinal well-being.

Senna (Senna alexandrina): Senna, containing anthraquinone glycosides, is an established laxative, effectively addressing constipation and assisting in bowel preparation for diagnostic procedures such as colonoscopies.

Slippery Elm (Ulmus rubra): Slippery elm, with mucilage, tannins, and flavonoids, soothes and heals mucous membranes throughout the gastrointestinal tract. It offers relief from conditions like ulcers, colitis, gastritis, acid reflux, and heartburn.

Wild Dagga (Leonotis leonurus): Wild Dagga contains leonurine and other constituents that aid in detoxification by eliminating toxins and heavy metals, promoting digestive system health.

Wild Yam (Dioscorea villosa): Wild yam, featuring diosgenin, a precursor to steroid hormones, may offer support for individuals with conditions like diverticulitis, celiac disease, and Crohn's disease.

Yarrow (Achillea millefolium): Yarrow, with its flavonoids, alkaloids, and tannins, possesses potent anti-inflammatory properties and wound-healing capabilities. This can benefit individuals with colitis, fever, upset stomach, infections, and wounds.

Yellow Dock Root (Rumex crispus): Yellow Dock root, rich in anthraquinones, increases hydrochloric acid (HCL) production, making it suitable for individuals with overactive digestion, excessive appetite, reflux, and excessive salivation. It aids in maintaining a balanced digestive system.

These herbal ingredients collectively contribute to a comprehensive Digestive and Colon supplement, addressing a spectrum of gastrointestinal concerns through their distinctive properties and constituents.